Cisplatin hund

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August undefined, 2024

WebCisplatin is approved to be used alone or with other drugs to treat: Bladder cancer. It is used alone in patients with advanced cancer that cannot be treated with other therapies, such as surgery or radiation therapy. Ovarian cancer that has spread to other parts of the body. It is used with other drugs in patients who have already had surgery ... WebCisplatin is a chemotherapy medication used to treat a number of cancers. [2] These include testicular cancer, ovarian cancer, cervical cancer, bladder cancer, head and neck cancer, …

Cisplatin nephrotoxicity - UpToDate

WebDec 2, 2024 · Cisplatin is a commonly used chemotherapeutic drug for cancer treatment, but its nephrotoxicity may lead to the deterioration of renal function. Previous work has been focused on cisplatin-induced acute kidney disease, whereas the mechanism of chronic kidney disease after cisplatin chemotherapy is largely unknown. WebCisplatin Injection infusion concentrate is a clear, colorless, sterile aqueous solution available in amber vials. Each 50 mL or 100 mL amber vial of infusion concentrate … chronicle information resources ltd

Cisplatin Uses, Side Effects & Warnings - Drugs.com

WebOct 22, 2024 · Cisplatin is an alkylating agent which induces DNA damage through the formation of cisplatin-DNA adducts, leading to cell cycle arrest and apoptosis. In the management of advanced OSCC, cisplatin-based chemotherapy or chemoradiotherapy has been considered as the first-line treatment. WebOct 7, 2024 · Cisplatin is one of the most widely used chemotherapeutic drugs in the treatment of a wide range of pediatric and adult malignances. However, it has various side effects which limit its use. Cisplatin mouse models are widely used in studies investigating cisplatin therapeutic and toxic effects. WebCisplatin injection is indicated as a single agent for patients with transitional cell bladder cancer which is no longer amenable to local treatments, such as surgery and/or … chronicle ingestion api

CISplatin: Dosage, Mechanism/Onset of Action, Half …

Cisplatin 12. Modes of Action of Cisplatin - Chemistry LibreTexts

WebFeb 16, 2024 · Warnings. Cisplatin can affect your nervous system, increase your risk of bleeding or infection, or harm your kidneys.. Call your doctor if you have a fever, mouth sores, cough, sore throat, unusual bleeding or bruising, hearing problems, numbness or tingling in your hands or feet, little or no urinating, swelling or rapid weight gain, or … Webof cisplatin with urine from healthy subjects, except that the proportions are different. The parent compound, cisplatin, is excreted in the urine and accounts for 13% to 17% of the dose excreted within one hour after administration of 50 mg/m2. The mean renal clearance of cisplatin exceeds creatinine clearance and is 62 and chronicle in a sentence examplesWebCisplatin is a chemotherapy drug which is used to treat cancers including: sarcoma, small cell lung cancer, germ cell tumors, lymphoma, and ovarian cancer. While it is often … chronicle information resources

"WebOct 13, 2024 · Cisplatin is nephrotoxin that can cause both acute kidney injury and chronic kidney disease. Accumulation of cisplatin in renal tubular cells induces various intracellular stresses, including... " - Cisplatin hund

Cisplatin hund

Cisplatin (Intravenous Route) Side Effects - Mayo Clinic

WebCisplatin for i njection has been administered at 75 mg/m 2 to 100 mg/m 2 intravenously per cycle once every 3 to 4 weeks o n Day 1. Other dos es and combination regimens have been used. 2.4 Advanced Bladder Cancer . Cisplatin for i njection has been administered at 50 mg/m 2 to 70 mg/m 2 intravenously per cycle once every 3 to 4 weeks. WebJan 5, 2024 · Cisplatin is a heavy metal complex containing two chloride atoms and two ammonia molecules surrounding a central platinum atom. Reviews of the actions, indications, and toxicities of these drugs in the dog are Studies in humans have demonstrated a more favorable response of patients with osteosarcoma to doxorubicin …

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WebCisplatin for injection is a highly emetogenic antineoplastic agent; premedicate with anti-emetic agents; without antiemetic therapy, marked nausea and vomiting occur in almost … WebJul 22, 2024 · It is important to note that for many malignancies, cisplatin is used in combination with other drugs that may also be nephrotoxic. Cellular toxicity — Cisplatin …

WebJun 13, 2005 · Cisplatin, cisplatinum or cis-diamminedichloroplatinum (II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes … WebOct 7, 2024 · Cisplatin is one of the most widely used chemotherapeutic drugs in the treatment of a wide range of pediatric and adult malignances. However, it has various …

WebMaterial Name: Cisplatin Solution for Injection - 0.5 and 1 mg/ml Revision date: 02-Jan-2007 Page 7 of 7 Version: 1.1 16. OTHER INFORMATION Reasons for Revision: Updated Section 2 - Composition / Information on Ingredients. Updated Section 3 - Hazard Identification. Updated Section 5 - Fire Fighting Measures. Web众所周知,肾衰竭的出现说明肾脏功能已经严重受损,而这种情况的发生,和慢性肾脏疾病发展到后期,引发肾脏功能部分或者全部丧失有关。其作为比较严重的病理状态,通常情况下难以治愈,应该高度重视,避免发展到这一步。那哪些因素会引发肾衰呢?一起来了解一下。

WebJun 17, 2016 · It can be diluted with DMSO or water. I diluted with DMSO. if you want value of IC50, final concentration could be from 200 microgram per mili litre to 12.5 (100, 50, 25, 12.5) with serial ...

WebCisplatin is administered to cancer patients intravenously as a sterile saline solution (that is, containing salt—specifically, sodium chloride). Once cisplatin is in the bloodstream, it remains intact due the relatively high concentration of chloride ions (~100 mM). chronicle in gcpWebFeb 16, 2024 · Generic name: cisplatin [ sis-PLA-tin ] Brand names: Platinol, Platinol-AQ, Platinol (Restricted Access) Dosage forms: intravenous powder for injection (50 mg), … chronicle in higher educationWebCisplatin is an intercalating agent that induces apoptosis of cancer cells, and it has been the most widely used drug in the first-line chemotherapy. However, the increase in cisplatin … chronicle insurance agency incWebJan 18, 2024 · The platinum-based drug cisplatin is a widely used first-line therapy for several cancers. Cisplatin interacts with DNA mainly in the form of Pt-d(GpG) di-adduct, which stalls cell proliferation ... chronicle in tagalogWebFeb 1, 2024 · Cisplatin injection is used to treat advanced cancer of the bladder, ovaries, or testicles. Cisplatin is an antineoplastic agent (cancer medicine). It interferes with the … chronicle in higher education jobs chronicle insuranceWebCisplatin / adverse effects* Dogs Dose-Response Relationship, Drug Female Male Plant Extracts / administration & dosage Plant Extracts / therapeutic use* Spices* Vomiting / … chronicle ingestion label