Csf2ra

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August undefined, 2024

WebHuman Gene CSF2RA (uc004cpp.2) Description: Homo sapiens colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA), transcript variant 3, mRNA. RefSeq Summary (NM_172246): WebDec 3, 2015 · CSF2RA expression also reduced the stemness of RUNX1-ETO bone marrow cells and inhibited their colony forming ability. To identify which region of the receptor …

CSF2RA / CD116 (NM_006140) ORF cDNA clone Expression …

WebMar 9, 2024 · Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder caused by recessive mutations in GM-CSF receptor subunit α/β genes (CSF2RA/CSF2RB, respectively) characterized by impaired GM-CSF-dependent surfactant clearance by alveolar macrophages (AMs) resulting in alveolar surfactant accumulation and … WebOct 21, 2024 · The expression of CSF2RA and IL1R2 in MAC sections was detected using antibodies of appropriate specificity (anti-CSF2RA, MBS711361; MyBioSource [San Diego, California, USA]; anti-IL1R2, LS-B377, LifeSpan [Seattle, Washington, USA]), and visualization system VECTASTAIN Elite ABC Kit (Vector Laboratories [Burlingame, … birmingham city v peterborough united

Characterization of CSF2RA mutation related juvenile …

WebCSF2RA, colony stimulating factor 2 receptor subunit alpha Vertebrate Orthologs 2 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog CSF2RA, colony stimulating factor 2 receptor subunit alpha. Synonyms alphaGMR, CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GMCSFR, GM-CSF-R … WebMar 21, 2024 · Cell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Acts by forming an heterodimeric … WebSep 20, 2024 · To test this, colony stimulating factor 2 receptor alpha (Csf2ra) knockout (KO) mice that lack GM-CSF signaling and wild-type (WT) mice models of intratracheal … d and w bathroom

CSF2RB - an overview ScienceDirect Topics

WebGenetic Factors. A series of reports have now established hereditary PAP as a newly described genetic disease caused by genetic mutations in CSF2RA or CSF2RB, which encode GM-CSF receptor α or β chains, respectively ( Fig. 70-3 ). 23-25,52,53 In some cases, the genes have been cloned, the defects reproduced in vitro, the signaling ... Webcolony stimulating factor 2 receptor alpha subunit : Nomenclature updated to reflect human and mouse nomenclature: 1299863: APPROVED: 2016-01-20: Csf2ra : colony … birmingham city v millwall fansWebLow affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of … d and w fresh market holland

"WebObjective: The aim of this study was to evaluate the relationship between cytokine production, GM-CSF receptor (CSF2RA), and IL-1 receptor (IL1R2) expression in … " - Csf2ra

Csf2ra

WebBy using this site, you agree to our Terms and Conditions Got it! WebThe protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a c ytokine which controls the production, differentiation, and …

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WebDescription: Homo sapiens colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA), transcript variant 11, non-coding RNA. RefSeq Summary (NR_027760): WebJan 5, 2024 · Orthologous to human CSF2RA (colony stimulating factor 2 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2024] Other designations. granulocyte-macrophage colony-stimulating factor receptor subunit alpha, GM-CSF-R-alpha, GM-CSFRalpha, GMCSFR-alpha, GMR-alpha, colony stimulating factor 2 receptor …

WebColony stimulating factor 2 receptor alpha, low-affinity (granulocyte-macrophage). CD116 molecule. Back to the top. Specifications Human CSF2RA isoform_1 (pUNO1 … WebDec 1, 2024 · To facilitate the translation of PMT therapy to human hPAP patients, a self-inactivating (SIN) lentiviral vector was generated expressing a codon-optimized human CSF2RA-cDNA driven from an EF1α short promoter (Lv.EFS.CSF2RA coop), and a series of nonclinical efficacy and safety studies were performed in cultured macrophage cell …

WebCSF2RA, “Colony stimulating factor 2 receptor alpha subunit (CD116)”, is a re-ceptor for GM-CSF (granulocyte-macrophage colony-stimulating factor), and plays a vital role for proliferation, differentiation and functional activation of hematopoietic cells such as macrophages and leukocytes . The absence of [1]

WebApr 8, 2024 · Harnessing the potential of this approach for gene therapy, we restored a disrupted Csf2ra gene in fetal liver monocytes and demonstrated their capacity to develop into alveolar macrophages in vivo. Altogether, we provide a platform for generation of immature alveolar macrophage-like precursors amenable for genetic manipulation, which …

WebMay 2, 2024 · The congenital form of pulmonary alveolar proteinosis due to colony stimulating factor 2 receptor alpha gene mutations is a rare disease with only a few … birmingham city v plymouthWebNov 26, 2014 · Juvenile pulmonary alveolar proteinosis (PAP) due to CSF2RA mutations is a rare disorder with only a few cases described worldwide. We identified nine children … d and w bassendeanhttp://www.informatics.jax.org/marker/MGI:1339754 d and w automotive jonesboro arkansasWebCSF2RA colony stimulating factor 2 receptor subunit alpha [ (human)] Gene ID: 1438, updated on 26-Oct-2024. Summary. The protein encoded by this gene is the alpha … birmingham city v peterboroughWebThe gene view histogram is a graphical view of mutations across CSF2RA. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. d and w bathWebHuman Gene CSF2RA (uc010ncv.2) Description: Homo sapiens colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) (CSF2RA), transcript variant 8, mRNA. RefSeq Summary (NM_001161530): d and w east beltlineWebOrder. Sequence variants and/or copy number variants (deletions/duplications) within the CSF2RA gene will be detected with >99% sensitivity. Variants classified as unknown … d and w bakery