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Designing materials to direct stem-cell fate

WebNov 8, 2012 · It is well-known that stem cells are tightly regulated by a combination of physical and chemical factors from their complex extracellular surroundings; thus, … WebNov 30, 2015 · The extracellular matrix, a microenvironment of proteins and polymers that surrounds and connects cells, impacts a range of cellular behaviors including differentiation. For about a decade, researchers have been able to direct the fate of stem cells by tuning the mechanical stiffness of synthetic microenvironments such as hydrogels. Stem cells ...

Designing biomaterials to direct stem cell fate - PubMed

WebSep 26, 2011 · MP Lutolf, PM Gilbert, HM Blau, Designing materials to direct stem-cell fate. Nature 462, 433–441 (2009). Crossref. PubMed. Google Scholar. 14. T Lecuit, PF Lenne, Cell surface mechanics and the control of cell shape, tissue patterns and morphogenesis. Nat Rev Mol Cell Biol 8, 633–644 (2007). WebNov 27, 2012 · It is well-known that stem cells are tightly regulated by a combination of physical and chemical factors from their complex extracellular surroundings; thus, … floor protection mitre 10 https://professionaltraining4u.com

Designing materials to direct stem-cell fate Nature

WebFeb 2, 2024 · Most design strategies for fabricating stem cell-laden tissue engineered scaffolds can be classified into one of the two categories. The first approach, top-down, focuses on designing the extracellular environment to contain the appropriate signals for guiding the differentiation of stem cells towards the lineage of choice. WebNov 8, 2012 · Biomaterials for controlling stem cell fate. Biomaterials for stem cells have become an important part of regenerative medicine because they can serve as a biomimetic platform for relevant biological studies. 3 Furthermore, these materials can ultimately be used as scaffolds for constructing artificial tissues or organs for clinical applications. To … WebNov 25, 2009 · Biomaterials are rapidly being developed to display and deliver stem-cell-regulatory signals in a precise and near-physiological fashion, and serve as powerful … floor protection mats office chairs

Designing materials to direct stem-cell fate. - Europe PMC

Category:Controlling stem cell fate with material design - PubMed

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Designing materials to direct stem-cell fate

Designing Biomaterials To Direct Stem Cell Fate ACS Nano

WebDec 3, 2009 · Biomaterials are rapidly being developed to display and deliver stem-cell-regulatory signals in a precise and near-physiological fashion, and serve as powerful … WebFeb 5, 2024 · Many studies aim to identify reliable stem cell–materials grafts for cardiac repair. However, due to a lack of mechanistic understanding of cardiac regeneration, ... Lutolf MP, Gilbert PM, Blau HM (2009) Designing materials to direct stem-cell fate. Nature 462(7272):433–441.

Designing materials to direct stem-cell fate

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WebOct 23, 2024 · Human pluripotent stem cells (hPSCs), such as embryonic stem cells (ESCs) 1 and induced pluripotent stem cells (iPSCs) 2, are important cell sources for regenerative therapies and modelling of ... WebApr 14, 2024 · This work therefore provides new insights into the fundamental understanding of cell-material interactions, and will have a profound impact on further designing materials to direct stem cell fate ...

WebNov 27, 2012 · As stem cells are a cornerstone of regenerative medicine, research efforts have been extensively focused on controlling their self-renewal and differentiation. It is … WebNYSCF Global Stem Cell Array® Repository / Stem Cell Search; Partnering & Alliances; Publications; Disease Focuses. Alzheimer’s Disease; Bone & Tissue Engineering; …

WebNov 8, 2012 · Search worldwide, life-sciences literature Search. Advanced Search Coronavirus articles and preprints Search examples: "breast cancer" Smith J"breast cancer" Smith J

WebDesigning materials to direct stem-cell fate Lutolf, Matthias P. ; Gilbert, Penney M. ; Blau, Helen M. Proper tissue function and regeneration rely on robust spatial and temporal …

WebMar 29, 2016 · Designing materials to direct stem-cell fate. Nature. 2009;462:433–41. Article Google Scholar Onoe H, Okitsu T, Itou A, Kato-Negishi M, Gojo R, Kiriya D, et al. Metre-long cell-laden microfibres exhibit tissue morphologies and functions. Nat Mater. 2013;12:584–90. Article Google ... great point nantucket beachWebNov 1, 2009 · Designing 3D materials to control stem-cell fate in vitro. Whereas 2D approaches allow well-controlled analysis of the impact on stem cells of individual … floor protection tray under freezerWebDesigning 3D materials to control stem-cell fatein vitro Whereas 2D approaches allow well-controlled analysis of the impact on stem cells of individual components of the … floor protection chair matsWebAug 10, 2014 · Stem cells regulate their fate by binding to, and contracting against, the extracellular matrix. ... H. M. Designing materials to direct stem-cell fate. Nature 462, 433–441 (2009). Article CAS ... great point nantucket permitWebNov 25, 2009 · Designing 3D materials to control stem-cell fate in vitro Whereas 2D approaches allow well-controlled analysis of the impact on … floor protection under washing machineWebApr 27, 2024 · Stem cells in contact with materials are able to sense their surface features, integrate extracellular matrix (ECM) protein cues through a signal transduction pathway, and ultimately direct cell fate decisions. However, discovering the interdisciplinary mechanisms of how stem cells respond to inherent material surface features still remains a … floor protection when decoratingWebTherefore, stem cells can be active components for materials nanoarchitectonics with delicate regulations of interactive information exchanges between materials and cells. Transmission of signals and information from material surface to living cells can induce complicated events of signal transductions and material conversions within the cells ... floor protection wood stove