Hif 1 alpha uniprot

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August undefined, 2024

Web27 de fev. de 2024 · UniProt Q16665 - HIF1A_HUMAN. Gene HIF1A Modification Unmodified View Product On Supplier's Website Request a Quote ... HIF1, BHLHE78, MOP1, PASD8, HIF-1A, HIF-1alpha, HIF1-ALPHA, HIF-1-alpha. View additional product information. Experiments from the literature. Loading published images for this product … WebImmunocytochemistry analysis of HIF1A in immersion fixed HeLa human cervical epithelial carcinoma cell line treated with DFOA. Samples were incubated in HIF1A monoclonal antibody (Product # MA1-16504) using a dilution of 1 µg/mL followed by donkey anti-rabbit secondary antibody and counterstained with DAPI (blue).

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Web13 de fev. de 2024 · HIF prolyl hydroxylases are oxygen sensors that regulate the stability of the hypoxia-inducible factors (HIFs) in an oxygen-dependent manner. Aragones et al. (2008) showed that loss of Phd1 expression in knockout mice lowers oxygen consumption in skeletal muscle by reprogramming glucose metabolism from oxidative to more anaerobic … WebUnder hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth … population of turkey bc 509

Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals ...

WebHIF-1-alpha 1 publication; HIF1-alpha 1 publication. Alternative names. ARNT-interacting protein; ... 1-826: UniProt: Hypoxia-inducible factor 1-alpha: BLAST Add. Sequence: Glycosylation: 18: UniProt (Microbial infection) N-beta-linked (GlcNAc) arginine 1 publication. Sequence: R: Modified residue: 247: Web12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent hydroxylation. Under normoxic conditions, … Web結構. 缺氧大部分需要氧氣呼吸的物種，都擁有保守序列HIF-1。其轉錄都有嚴格的調控機制。HIF-1是由一個α亞基和一個β亞基組成的異源蛋白二聚體，而β亞基是一種芳香烃受体核转位子（英语： Aryl hydrocarbon receptor nuclear translocator ）（ARNT）。 HIF-1屬於鹼性螺旋-環-螺旋（bHLH）家族中的PER-ARNT-SIM ... population of turkey bc 513

Anti-HIF1 alpha antibody (GTX30647) GeneTex

WebA fusion protein including amino acids 530 - 825 of the mouse HIF-1 alpha protein [UniProt# Q61221]. Purification Purified by antigen-affinity chromatography Conjugation … Web19 de set. de 2012 · Identification of Cys 255 in HIF-1 as a novel site for development of covalent inhibitors of HIF-1 /ARNT PasB domain ... Identification of Cys255 in HIF-1 … population of turkey bc 48WebThis kit recognizes Human HIF-1α in samples. No significant cross-reactivity or interference between Human HIF-1α and analogues was observed. Both intra-CV and inter-CV are < 10%. This ELISA kit applies to the in vitro quantitative determination of Human HIF-1α concentrations in serum, plasma and other biological fluids. population of turkey bc 512

"Web6 de out. de 2024 · HIF is a transcription factor that plays an essential role in the cellular response to low oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In immunity, infected and inflamed tissues are often hypoxic, and HIF helps immune cells adapt. HIF-α stabilization ca … " - Hif 1 alpha uniprot

Hif 1 alpha uniprot

Entry - *606424 - EGL9 FAMILY HYPOXIA-INDUCIBLE FACTOR 2; EGLN2 …

Web21 de mar. de 2024 · HIF1A (Hypoxia Inducible Factor 1 Subunit Alpha) is a Protein Coding gene. Diseases associated with HIF1A include Retinal Ischemia and Enchondromatosis, Multiple, Ollier Type.Among its related pathways are Signaling by PTK6 and Regulation of activated PAK-2p34 by proteasome mediated degradation.Gene … WebCrystal structure of a hydroxylated hif-1 alpha peptide bound to the pvhl/elongin-c/elongin-b complex . Experiment type: X-ray diffraction, resolution 2.00Å Release ... This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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WebHIF1A. Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 ( HIF-1) that is encoded by the HIF1A gene. [5] [6] [7] The Nobel Prize in Physiology or Medicine 2024 was awarded for the discovery of HIF. HIF1A is a basic helix-loop-helix PAS domain containing ... Web29 de fev. de 2004 · Hypoxia-inducible factor (HIF-1) is an oxygen-dependent transcriptional activator, which plays crucial roles in the angiogenesis of tumors and mammalian development. HIF-1 consists of a constitutively expressed HIF-1beta subunit and one of three subunits (HIF-1alpha, HIF-2alpha or HIF-3alpha). The s …

Web14 de abr. de 2024 · 1 Introduction. Worldwide, colorectal cancer (CRC) is the third most lethal malignant tumor and the fourth most frequently diagnosed malignant tumor (1, 2).The global incidence and mortality of CRC are increasing because of the continuously expanding and aging of the population with no differences between the sexes ().CRC accounts for … Web12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent …

WebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-HIF-1 alpha antibody [EPR16897] (ab179483) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – confirmed ... WebBHLHE78, HIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, HIF1A, MOP1, PASD8. ... UniProt ID (Human) Q16665. Show Less . About This Kit. The Human HIF1A ELISA …

WebUniProt : Q16665; Isotype : Rabbit IgG Clonality : Monoclonal; Price : $185/50μl, $299/100μl Availability : Ship next day Rank: Download datasheet [PDF] : Category. Primary Antibodies; ... HIF-1 alpha Antibody detects endogenous levels of total HIF-1 …

WebUniProt website fallback message If you are not seeing anything on this page, it might be for multiple reasons: You might have JavaScript disabled: make sure to ... population of turkey bc 52Web19 de mar. de 2002 · Disruption of the Hif-1 alpha/p300 interaction has been linked to attenuation of tumor growth. To delineate the structural basis for this interaction, ... population of turkey bc 516Web9 de mai. de 2002 · Crystal structure of a hydroxylated HIF-1 alpha peptide bound to the pVHL/elongin-C/elongin-B complex. ... Hypoxia-inducible factor 1 ALPHA: D: 34: N/A: Mutation(s): 1 : UniProt & NIH Common Fund Data Resources: Find proteins for Q16665 (Homo sapiens) Explore Q16665 . Go to UniProtKB: Q16665. PHAROS: Q16665. population of turkey bc 47WebCharacterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins. Biochem Biophys Res Commun 260, 557-561. Tanimoto, K., Makino, Y., Pereira, T., and Poellinger, L. (2000). Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein. population of turkey bc 537WebProduct Specific Information. MA1-516 detects hypoxia-inducible factor 1 alpha (HIF-1 alpha) from human, non-human primate, bovine, mouse and porcine cells. This antibody does not cross-react with ARNT or the related HIF-2 alpha. MA1-516 has been successfully used in Western blot, immunofluorescence, immunoprecipitation, immunocytochemistry ... population of turkey bc 527http://www.abways.com/showproduct.asp?cid=CY5197 population of turkey bc 603WebAnti-HIF-1 alpha antibody [H1alpha67] (ab1) ... Information by UniProt; ... Immunohistochemical analysis of paraffin-embedded human lung tissue labeling Neurogranin with ab273444 at 1/10000 (0.111 ug/ml) dilution followed by a ready to use LeicaDS9800 (Bond® Polymer Refine Detection) was used. population of turkey bc 528