http://www.iciba.com/word?w=coupon Web17 rows · Phosphorothioate Bond. The phosphorothioate (PS) bond substitutes a sulfur atom for a non-bridging oxygen in the phosphate backbone of an oligo. This modification …
Phosphorothioate-based DNA recombination: an enzyme ... - BioTechniques
WebJan 14, 2014 · The phosphorothioate (PS) bond substitutes a sulfur atom for a non-bridging oxygen in the phosphate backbone of an oligonucleotide. Approximately 50% of the time (due to the 2 resulting stereoisomers that can form), PS modification renders the internucleotide linkage more resistant to nuclease degradation. Therefore, IDT … WebOct 4, 2024 · Synthetic phosphorothioate (PT) internucleotide linkages, in which a nonbridging oxygen is replaced by a sulphur atom, share similar physical and chemical … clayton county high schools
Oligonucleotide modifications: Choose the right mod IDT
WebFrom Wikipedia, the free encyclopedia. Thiophosphates(or phosphorothioates, PS) are chemical compoundsand anions with the general chemical formulaPS. 4−xO3−. x(x= 0, 1, … WebApr 11, 2012 · Phosphorothioate bonds. The phosphorothioate (PS) bond substitutes a sulfur atom for a non-bridging oxygen in the phosphate backbone of an oligo. This modification renders the internucleotide linkage resistant to nuclease degradation. Phosphorothioates can be introduced at either the 5’- or 3’-end of the oligonucleotide to … WebPhosphorothioates, essential components of therapeutic oligonucleotides. Phosphorothioates have found their usefulness in the general area of oligonucleotide … clayton county health department ga