WebApr 18, 2024 · Propofol is the most commonly used drug for sedation in infancy, though the risk of inducing respiratory arrest and systemic hypotension is especially relevant in prematurely and term-born infants less than 60 weeks postconceptional age. 10-12 The alpha-2 receptor-agonist dexmedetomidine showed high efficacy as a sole sedative in … WebNov 29, 2024 · Opioids, such as remifentanil and fentanyl, are options that provide analgesia via agonism of G-protein-coupled μ-opioid receptors. Remifentanil produces favorable …
Pediatric Focused Safety Review Precedex (dexmedetomidine)
WebDexmedetomidine (Precedex ... children includes infants, ranging in age from 1 to 24 months, following surgery for congenital heart disease. The authors reported a median … WebJul 1, 2024 · Dexmedetomidine infusion combined with remifentanil infusion is also being used in infants (younger than 1 yr) undergoing lower limb/lower abdominal surgery expected to last longer than 2 h in another pilot study. 178 A loading dose of dexmedetomidine 0.6 μg/kg and 1 μg/kg remifentanil was followed by an infusion rate of dexmedetomidine 1 to … scala st helens
Dexmedetomidine Use in Infants Undergoing Cooling Due to …
WebJan 9, 2024 · In a controlled clinical trial, PRECEDEX was compared to midazolam for ICU sedation exceeding 24 hours duration in adult patients. Key treatment emergent adverse … Webry function at sedative doses, facilitating early extubation and fast-track postoperative care. There are little pharmacokinetic data regarding newborns who have immature drug … WebDec 3, 2024 · Premature infants were started on dexmedetomidine at a later chronological age than term infants (41 vs 9 days, P = 0.004). Of 18 patients receiving an opioid infusion … scala step youth