Shoc2 antibody

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August undefined, 2024

WebThis antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients … WebSHOC2 KIAA0862, SOC-2, SOC2, SUR-8, SUR8 This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade.

Anti-SHOC2 antibody (GTX130206) GeneTex

WebMolecularly, SHOC2 is a scaffold protein that brings together activated Ras (activated via G-protein coupled receptors and the interaction of GTP to GDP) and Raf, which then … Webbody, speciﬁcally recognizing phospho-Thr507 of SHOC2. Using this antibody, we found that pSHOC2-Thr507 and total SHOC2 were accumulated upon the treatment of MLN4924 in a dose-dependent manner in FBXW7 wild-type cells but to a much lesser degree in FBXW7 null cells (Figures S2A and S2B). To identify signal that could trigger SHOC2-Thr507 ... dunaj k vasim sluzbam markiza

(PDF) HUWE1 Is a Molecular Link Controlling RAF-1

Web24 Jan 2024 · Immunocytochemical analysis using FlaA antibody showed positive signal in the hemocytes from V. ... In addition, SHOC2 recruits enzymes, including the catalytic subunit of the protein phosphatase 1 and E3 ubiquitin ligase HUWE1, into the complex to fine-tune ERK signaling [38,39]. Web2.2.4 Antibody list 44 Chapter 3 45 3.1 SHOC2 is required for the malignant properties of growth in RAS mutant cells 46 3.1.1 Introductory statement 46 3.1.2 SHOC2 is required for basal ERK-pathway signalling in MDA-MB-231 cells 46 3.1.3 SHOC2 is required for the 3D-anchorage-independent, but not 2D-adhered growth of MDA-MB-231 cells 47 WebPVDF membrane was probed with 2 µg/mL of Mouse Anti-Human FBXW7/Cdc4 Monoclonal Antibody (Catalog # MAB7776) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018 ). A specific band was detected for FBXW7/Cdc4 at approximately 110 kDa (as indicated). This experiment was conducted under reducing … dunaj k vašim službám online free

Shoc2 controls ERK1/2-driven neural crest development by …

Localized immune surveillance of primary melanoma in the skin ...

WebSur-8 Antibody - #DF12234 (2) WB; IHC; 1 /2. Western blot analysis of extracts from U-251 cells, using Sur-8 Antibody. DF12234 at 1/100 staining Rat liver tissue by IHC-P. Previous Next. 产品: rc su 26WebDetect, measure, and explore your target protein's identity and function using our products: peptides, recombinant proteins, antibodies, ELISA kits, NGS, and more. dunaj k vasim sluzbam pocet casti

"Web12 Dec 2013 · SHOC2 is mutated in Noonan syndrome and plays a key role in the activation of the ERK-MAPK pathway, which is upregulated in the majority of human cancers. SHOC2 functions as a PP1-regulatory protein and as an effector of MRAS. Here we show that SHOC2 and MRAS form a complex with SCRIB, a polarity protein with tumor suppressor … " - Shoc2 antibody

Shoc2 antibody

Single-domain antibodies for functional targeting of the signaling ...

WebPrEST Antigen SHOC2 [Catalog No.: ATL-APrEST94686] Toggle menu. Compare ; Phone: 760-431-4600 / Fax: 760-431-4604; Sign in or Register; Cart 0. Search. CURRENT PROMOTIONS. ... Primary Antibodies; Marfan syndrome . All Marfan syndrome; Labeled Proteins; Abs For Paraffin Embedded Tissue; Primary Antibodies; ELISAs from CusaBio; WebSHOC2 acts as a positive modulator of the RAS-MAPK signaling cascade, which is elicited by EGL-15 and LET-23 and mediated by LET-60. SHOC2 together with protein …

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WebGet Rockland's Anti-SHOC2 (RABBIT) Antibody - 600-401-EJ4 for ELISA, IHC, WB. Reacts with Human. Order online now! WebAnti-SHOC2 Rabbit Polyclonal Antibody (107268-T32), manufactured by Sino Biological is validated in WB. Custom antibody services and bulk production also available. To learn more comprehensive our antibody product information including immunogen, specificity, and more, you can read all details here.

Web24 Jan 2024 · Shoc2 recognizes bacterial flagellin and mediates antibacterial Erk/Stat signaling in an invertebrate. Bao-Rui Zhao, Roles Data curation ... Rabbit anti-FlaA antibodies and goat anti-rabbit Alexa Fluor 594 was used to visualize signal and Dio probe was used to stain the cell membrane. DAPI was used to stain the nuclei. Scale bar = 10 μm. WebCompare Anti-Shoc2 Antibody Products from leading suppliers on Biocompare. View specifications, prices, citations, reviews, and more.

Web公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）! 抗体描述：产品名称：Rabbit anti-TBL2 Polyclonal Antibody 产品别名：TBL2抗体宿主：Rabbit 反应种属：Human WebCBA using live cells transfected with full-length human MOG and employing Fc-specific detection antibodies are the gold standard for anti-MOG antibody testing.[24] Serum is the sp

WebMedium consistency between antibody staining and RNA expression data. WESTERN BLOT i A Western blot analysis is performed on a panel of human tissues and cell lines to …

Web1 Feb 2024 · This study illustrates that Shoc2 single-domain antibodies can be used to understand functional mechanisms governing complex multiprotein signaling modules and have promise in application for therapies that require modulation of the ERK1/2-associated diseases. Introduction dunaj k vasim sluzbam s02e03Web13 Jul 2024 · SHOC2 Ile173 (Met173 in WT SHOC2) fills a hydrophobic space produced by SWI, SWII and SHOC2 LRR domains. SHOC2 Gln269/His270 resides at the interface of all … rc su-27WebTyrosine-phosphorylated proteins were detected (as indicated) using 50 µg/mL of Mouse Anti-Phospho-Tyrosine Monoclonal Antibody (Catalog # MAB1676). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system. Immunocytochemistry View Larger. Phospho-Tyrosine in A431 Human Cell Line. rc su33WebMolecularly, SHOC2 is a scaffold protein that brings together activated Ras (activated via G-protein coupled receptors and the interaction of GTP to GDP) and Raf, which then facilitates the transfer of the phospho-Raf phosphate to other proteins for the activation of the MAP Kinase pathway for gene activation. dunaj k vasim sluzbam onlineWebAntibody information for antibodies HPA009164 and HPA048134 used in analysis of ENSG00000108061 / SHOC2 (KIAA0862, SOC-2, SOC2, SUR-8, SUR8) We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. dunaj k vasim sluzbam wikiWebAnti-SHOC2 Antibody ABS461 Detect Leucine-rich repeat protein SHOC-2 using this rabbit polyclonal antibody, Anti-SHOC2 Antibody validated for use in western blotting & IHC. - Find MSDS or SDS, a COA, data sheets and more information. It appears that your browser has JavaScript disabled. This Website requires your browser to be JavaScript enabled. rc su 30 plansWeb25 Mar 2024 · SHOC2 protein participates in protein binding / transferase activity in the fibroblast growth factor receptor signaling pathway and Ras protein signal transduction. It is a widely expressed protein composed almost entirely of leucine-rich repeats (LRR), with a lysine-rich sequence at the amino terminus and cytoplasmically localized. rc su-30